Sunscreen use and malignant melanoma
Författare
Summary, in English
In a new population-based, matched, case-control study from southern Sweden of 571 patients with a first diagnosis of cutaneous malignant melanoma, between 1995 and 1997, and 913 healthy controls aged 16 to 80 years, the association between sunscreen use and malignant melanoma was evaluated. The median sun protection factor (SPF) used by both cases and controls was 6, range 2 to 25. Sunscreen users reported greater sun exposure than non-users. Persons who used sunscreens did not have a decreased risk of malignant melanoma. Instead, a significantly elevated odds ratio (OR) for developing malignant melanoma after regular sunscreen use was found, adjusted for history of sunburns, hair color, frequency of sunbathing during the summer, and duration of each sunbathing occasion ¿OR = 1.8, 95% confidence interval (CI) 1.1-2.9]. The OR was higher in subjects who reported that sunscreen use enabled them to spend more time sunbathing (adjusted OR = 8.7, 95% CI 1.0-75.8 for always vs. never use). The association appeared to hold for subjects who did not suffer from sunburns while using sunscreens, for subjects who used SPF of 10 or lower, and among men. The pattern of a significantly increased melanoma risk was seen only for lesions of the trunk. Our results are probably related mainly to earlier sunscreens of low SPF. They substantiate the hypothesis that sunscreen use, by permitting more time sunbathing, is associated with melanoma occurrence.
Publiceringsår
2000-07-01
Språk
Engelska
Sidor
145-150
Publikation/Tidskrift/Serie
International Journal of Cancer
Volym
87
Issue
1
Dokumenttyp
Artikel i tidskrift
Förlag
John Wiley & Sons Inc.
Ämne
- Cancer and Oncology
Nyckelord
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Case-Control Studies
- Female
- Humans
- Male
- Melanoma
- Middle Aged
- Odds Ratio
- Phenotype
- Risk
- Skin Neoplasms
- Sunscreening Agents
- Surveys and Questionnaires
- Sweden
Status
Published
Forskningsgrupp
- Lund Melanoma Study Group
ISBN/ISSN/Övrigt
- ISSN: 0020-7136