P¹/P² genotyping of known and novel null alleles in the P1PK and GLOB histo-blood group systems.

Summary, in English

The rare but clinically important null phenotypes of the P1PK and GLOB blood group systems are due to alterations in A4GALT and B3GALNT1, respectively. A recently identified single-nucleotide polymorphism in Exon 2a of A4GALT predicts the common P1 and P2 phenotypes but rare variants have not been tested.

• Författare: Julia Westman; Åsa Hellberg; Thierry Peyrard; Hein Hustinx; Britt Thuresson; Martin L Olsson
• Avdelning/ar: Avdelningen för hematologi och transfusionsmedicin; Transfusionsmedicin
• Publiceringsår: 2013
• Språk: Engelska
• Sidor: 2928-2939
• Publikation/Tidskrift/Serie: Transfusion
• Volym: 53
• Issue: 11
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/23927681?dopt=Abstract; http://dx.doi.org/10.1111/trf.12355
• Dokumenttyp: Artikel i tidskrift
• Förlag: Wiley-Blackwell
• Ämne: Hematology
• Aktiv: Published
• Forskningsgrupp: Transfusion Medicine
• ISBN/ISSN/Övrigt: ISSN: 1537-2995