2-Bromoethyl glycosides for synthesis of glycoconjugates on solid support
Författare
Summary, in English
2-Bromoethyl glycosides can easily and in high yields be transformed into sulfones by treatment with a suitable thiol followed by oxidation with mCPBA. The observation that the so formed sulfones were cleaved by treatment with NaOMe/MeOH was used to design a new safety catch linker for synthesis of glycoconjugates on solid support. (C) 2005 Elsevier Ltd. All rights reserved.
Avdelning/ar
Publiceringsår
2005
Språk
Engelska
Sidor
2421-2429
Publikation/Tidskrift/Serie
Tetrahedron
Volym
61
Issue
9
Dokumenttyp
Artikel i tidskrift
Förlag
Elsevier
Ämne
- Organic Chemistry
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0040-4020