Plasma levels of apolipoprotein M in normal and complicated pregnancy.
Författare
Summary, in English
Apolipoprotein M (apoM) is mainly associated with high-density lipoprotein in human plasma. Despite several studies suggesting apoM as an anti-atherogenic, its function is not yet fully understood. Plasma apoM was measured in normal pregnancies at four different gestational ages and in the postpartum period to investigate whether the concentration of apoM changes during pregnancy. In addition, apoM was measured at 13 weeks in women who subsequently developed preeclampsia, gestational diabetes, recurrent miscarriage, or small-for-gestational age babies, and in women with uncomplicated pregnancies. The plasma concentrations of apoM increased during pregnancy to reach highest levels in the postpartum period. Thus, plasma apoM in non-pregnant women was around 0.77 micromol/l, 0.88 micromol/l at 40 gestational weeks, and 1.05 micromol/l in the postpartum period (p < 0.0001). No differences in plasma concentrations of apoM were found among the studied pregnancy complications.
Publiceringsår
2010
Språk
Engelska
Sidor
1214-1217
Publikation/Tidskrift/Serie
Acta Obstetricia et Gynecologica Scandinavica
Volym
89
Issue
9
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Wiley-Blackwell
Ämne
- Obstetrics, Gynecology and Reproductive Medicine
Nyckelord
- Pregnancy Complications: blood
- Pregnancy: blood
- Apolipoproteins: blood
- Postpartum Period: blood
Status
Published
Forskningsgrupp
- Clinical Chemistry, Malmö
ISBN/ISSN/Övrigt
- ISSN: 1600-0412