Amperometric In Vitro Monitoring of Penetration through Skin Membrane
Författare
Summary, in English
The aim of this study was to demonstrate that penetration of quercetin, hydrogen peroxide and ascorbic acid through skin membranes can be monitored amperometrically. Skin membrane was fixed on the top of chemically modified electrodes and penetration of the appropriate compound was registered as electrode current. The methodology allows the study of penetration from solution as well as from pharmaceutical creams. From real-time measurements of electrode current, fluxes and diffusion coefficients of mentioned compounds in skin membranes have been estimated.
Avdelning/ar
- Cellpatologi, Malmö
- Department of Food Technology, Engineering and Nutrition
- Centrum för analys och syntes
Publiceringsår
2015
Språk
Engelska
Sidor
111-117
Publikation/Tidskrift/Serie
Electroanalysis
Volym
27
Issue
1
Dokumenttyp
Artikel i tidskrift
Förlag
John Wiley & Sons Inc.
Ämne
- Cancer and Oncology
Nyckelord
- Penetration
- Transdermal delivery
- Amperometry
- Quercetin
- Hydrogen
- peroxide
- Ascorbic acid
- Skin membrane
Status
Published
Forskningsgrupp
- Cell Pathology, Malmö
ISBN/ISSN/Övrigt
- ISSN: 1040-0397