Differing pattern of ambulatory blood pressure in very elderly men expresses dynamics in atherosclerotic load in the senescence.
Författare
Summary, in English
To assess an impact of vascular risk factors on ambulatory blood pressure measurement (ABPM) in the elderly, we followed up a population-based cohort of men from 68 until 82 years, when 104 survivors underwent ABPM. Results. At age 68, hypertension and high clinic blood pressure (CBP) did not predict ABPM level. Smoking and low ankle-brachial index (ABI) predicted higher ABPM variability and pulse pressure (PP), but not absolute ABPM values. At age 82, hypertension, high or increasing CBP, strongly positively correlated with all variables of ABPM. Carotid stenosis, low or declining ABI during followup, correlated with higher nocturnal ABPM and PP. Concluding. Hypertension and vascular risk factors in a cohort of 68-year-old men do not result in higher ABPM at age 82, possibly due to inflection point in their pressure development. Higher ABPM reflects instead an increasing CBP and aggravating atherosclerosis during the preceding decade in that part of the cohort with previously favorable risk factor status.
Avdelning/ar
- EpiHealth: Epidemiology for Health
- Geriatrik
- Geriatric Medicine
Publiceringsår
2012
Språk
Engelska
Publikation/Tidskrift/Serie
International Journal of Hypertension
Volym
2012
Issue
Dec 18
Fulltext
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Hindawi Limited
Ämne
- Cardiac and Cardiovascular Systems
Status
Published
Forskningsgrupp
- Geriatrics
- Geriatric Medicine
ISBN/ISSN/Övrigt
- ISSN: 2090-0392