Flow field-flow fractionation: Critical overview.
Författare
Summary, in English
This overview regards some critical issues in performing flow field-flow fractionation (flow FFF, FlFFF, AF4, HF-FlFFF, HF5). It includes the channel thickness, void time, channel-flow parabolic profile, channel-flow velocity gradient, uniformity of the cross-flow, sample injection time, relaxation/focusing time, width of sample starting zone, retention level, theoretical and experimental zone broadening, hydrodynamic threshold immobilisation/re-mobilisation, sample loss and adsorption, membrane fouling, sample mass overloading, problems with symmetrical channels, non-spherical sample particles, and method development. Good method development practice (GMDP) and good fractogram practice (GFP) is suggested.
Avdelning/ar
Publiceringsår
2013
Språk
Engelska
Sidor
97-112
Publikation/Tidskrift/Serie
Journal of Chromatography A
Volym
1287
Dokumenttyp
Artikel i tidskrift
Förlag
Elsevier
Ämne
- Chemical Sciences
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0021-9673