Regulation of cysteinyl leukotriene receptor 2 expression-a potential anti-tumor mechanism.

Summary, in English

The cysteinyl leukotrienes receptors (CysLTRs) are implicated in many different pathological conditions, such as inflammation and cancer. We have previously shown that colon cancer patients with high CysLT(1)R and low CysLT(2)R expression demonstrate poor prognosis. Therefore, we wanted to investigate ways for the transcriptional regulation of CysLT(2)R, which still remains to be poorly understood.

• Författare: Cecilia Magnusson; Astrid Bengtsson; Minghui Liu; Jian Liu; Yvonne Ceder; Roy Ehrnström; Anita Sjölander
• Avdelning/ar: Cellpatologi, Malmö; Klinisk kemi, Malmö; Patologi, Malmö; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publiceringsår: 2011
• Språk: Engelska
• Publikation/Tidskrift/Serie: PLoS ONE
• Volym: 6
• Issue: 12
• Fulltext: - 754 kB; Download statistics
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/22194989?dopt=Abstract; http://dx.doi.org/10.1371/journal.pone.0029060
• Dokumenttyp: Artikel i tidskrift
• Förlag: Public Library of Science (PLoS)
• Ämne: Cancer and Oncology
• Status: Published
• Forskningsgrupp: Cell Pathology, Malmö; Clinical Chemistry, Malmö; Pathology, Malmö
• ISBN/ISSN/Övrigt: ISSN: 1932-6203