The Potential of MicroRNAs as Prostate Cancer Biomarkers.

Summary, in English

Short noncoding RNAs known as microRNAs (miRNAs) control protein expression through the degradation of RNA or the inhibition of protein translation. The miRNAs influence a wide range of biologic processes and are often deregulated in cancer. This family of small RNAs constitutes potentially valuable markers for the diagnosis, prognosis, and therapeutic choices in prostate cancer (PCa) patients, as well as potential drugs (miRNA mimics) or drug targets (anti-miRNAs) in PCa management.

• Författare: Linda Fabris; Yvonne Ceder; Arul M Chinnaiyan; Guido W Jenster; Karina D Sorensen; Scott Tomlins; Tapio Visakorpi; George A Calin
• Avdelning/ar: Medicinsk molekylärbiologi; Avdelningen för translationell cancerforskning; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publiceringsår: 2016-01-21
• Språk: Engelska
• Sidor: 312-322
• Publikation/Tidskrift/Serie: European Urology
• Volym: 70
• Issue: 2
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/26806656?dopt=Abstract; http://dx.doi.org/10.1016/j.eururo.2015.12.054
• Dokumenttyp: Artikel i tidskrift
• Förlag: Elsevier
• Ämne: Urology and Nephrology
• Status: Published
• Forskningsgrupp: Medical Molecular Biology
• ISBN/ISSN/Övrigt: ISSN: 1873-7560