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Influence of Nonuniform Channel Width Distribution in Porous Silicon High Aspect Ratio Parallel Channel Micro Reactors

  • Thomas Laurell
  • Johan Nilsson
  • Klavs F. Jensen
  • D. Jed Harrison
  • Jörg P. Kutter
Publiceringsår: 2005
Språk: Engelska
Sidor: 629-631
Publikation/Tidskrift/Serie: [Host publication title missing]
Volym: 1
Dokumenttyp: Konferensbidrag
Förlag: Royal Society of Chemistry


The paper focuses on the fact that, since the flow rate in parallel channels relies strongly on the channel width, the combination may lead to inaccurate results if errors in the fabrication process lead to an uneven distribution of channel widths. Parallel channel enzyme reactors were designed with channel widths distributed normally with different degrees of standard deviation. The reactors were then evaluated with regard to dispersion and to catalytic effect of the immobilised enzyme. It was shown that for lower concentrations the catalytic efficiency decreased significantly even for small variations in the distribution of channel widths and reactors with poor homogeneity in channel widths also diluted the sample more than the others.


  • Medical Engineering
  • dispersion
  • IMER
  • keywords: microreactor
  • porous silicon


8th International Conference on Miniaturized System in Chemistry and Life Science
  • ISBN: 0-85404-643-7

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