Antiproliferative effects of peracetylated naphthoxylosides.
Författare
Summary, in English
The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs. Our data show increased antiproliferative activity upon peracetylation, but a loss of selectivity towards T24 cells.
Avdelning/ar
Publiceringsår
2009
Språk
Engelska
Sidor
1763-1766
Publikation/Tidskrift/Serie
Bioorganic & Medicinal Chemistry Letters
Volym
19
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Elsevier
Ämne
- Medicinal Chemistry
Status
Published
Forskningsgrupp
- Glycobiology
ISBN/ISSN/Övrigt
- ISSN: 0960-894X