Fifteen-Piconewton Force Detection from Neural Growth Cones Using Nanowire Arrays
Författare
Summary, in English
We used epitaxially grown monodisperse nanowire arrays to measure cellular forces with a spatial resolution of 1 mu m. Nerve cells were cultured on the array and cellular forces were calculated from the displacement of the nanowire tips. The measurements were done in situ on live cells using confocal microscopy, Forces down to 15 pN were measured on neural growth cones, showing that this method can be used to study the Fine details of growth-cone dynamics.
Publiceringsår
2010
Språk
Engelska
Sidor
782-787
Publikation/Tidskrift/Serie
Nano Letters
Volym
10
Issue
3
Dokumenttyp
Artikel i tidskrift
Förlag
The American Chemical Society (ACS)
Ämne
- Nano Technology
Nyckelord
- neuron
- nanowire
- picoNewton
- Mechanosensing
- cellular force
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1530-6992