Treatment with pioglitazone induced significant, reversible mitral regurgitation
Författare
Summary, in English
There has in recent years been great concern about possible cardiac side effects of thiazolidinediones ( TZDs). We present a case-report of a 60 year-old male who developed significant mitral regurgitation during six months treatment with pioglitazone in parallel with laboratory indications of fluid retention. Echocardiography six months after discontinuation of medication showed regression of mitral regurgitation and the laboratory parameters were also normalized. It is noteworthy that six months treatment with pioglitazone could induce significant valve dysfunction, which was reversible, and this underlines the importance of carefully monitoring patients when placing them on treatment with TZDs.
Publiceringsår
2008
Språk
Engelska
Publikation/Tidskrift/Serie
Cardiovascular Diabetology
Volym
7
Issue
12
Dokumenttyp
Artikel i tidskrift
Förlag
BioMed Central (BMC)
Ämne
- Endocrinology and Diabetes
- Radiology, Nuclear Medicine and Medical Imaging
Status
Published
Forskningsgrupp
- Genomics, Diabetes and Endocrinology
- Clinical Physiology, Malmö
ISBN/ISSN/Övrigt
- ISSN: 1475-2840