NMR solution structure of calerythrin, an EF-hand calcium-binding protein from Saccharopolyspora erythraea
Författare
Summary, in English
The structure of calerythrin, a prokaryotic 20 kDa calcium-binding protein has been determined by solution NMR spectroscopy. Distance, dihedral angle, J coupling, secondary chemical shift, residual dipolar coupling and radius of gyration restraints reveal four EF-hand motifs arranged in a compact globular structure. A tight turn in the middle of the amino acid sequence brings the two halves, each comprising a pair of EF-hands, close together. The structural similarity between calerythrin and the eukaryotic sarcoplasmic calcium-binding proteins is notable.
Avdelning/ar
Publiceringsår
2003
Språk
Engelska
Sidor
2505-2512
Publikation/Tidskrift/Serie
European Journal of Biochemistry
Volym
270
Issue
11
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Wiley-Blackwell
Ämne
- Physical Chemistry
Nyckelord
- calcium-binding
- calerythrin
- NMR
- structure
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0014-2956