The synthesis of bicyclo[2.2.2]octan-2,6-dione revisited
Författare
Summary, in English
The cyclisation conditions for the formation of bicyclo[2.2.2]octan-2,6-di one (1) from 3-substituted cyclohexanones 2 and 3 have been re-investigated. Use of a medium consisting of isobutyric anhydride and trifluoroacetic acid resulted in a simplified and reproducible method for large-scale synthesis of this compound.
Publiceringsår
2006
Språk
Engelska
Sidor
3527-3530
Publikation/Tidskrift/Serie
Synthesis
Issue
20
Dokumenttyp
Artikel i tidskrift
Förlag
Oxford Polytechnic, Oxford
Ämne
- Organic Chemistry
- Industrial Biotechnology
Nyckelord
- carboxylic acids
- diketones
- bicyclic compounds
- cyclisations
- anhydrides
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0039-7881