Animal snoRNAs and scaRNAs with exceptional structures
Författare
Summary, in English
The overwhelming majority of small nucleolar RNAs (snoRNAs) fall into two clearly defined classes characterized by distinctive secondary structures and sequence motifs. A small group of diverse ncRNAs, however, shares the hallmarks of one or both classes of snoRNAs but differs substantially from the norm in some respects. Here, we compile the available information on these exceptional cases, conduct a thorough homology search throughout the available metazoan genomes, provide improved and expanded alignments, and investigate the evolutionary histories of these ncRNA families as well as their mutual relationships.
Avdelning/ar
Publiceringsår
2011
Språk
Engelska
Sidor
938-946
Publikation/Tidskrift/Serie
RNA Biology
Volym
8
Issue
6
Dokumenttyp
Artikel i tidskrift
Förlag
Taylor & Francis
Ämne
- Cancer and Oncology
Nyckelord
- box C/D
- boxH/ACA
- scaRNA
- evolution
- secondary structure
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1547-6286