Platelet secretion of CXCL4 is Rac1-dependent and regulates neutrophil infiltration and tissue damage in septic lung damage.
Författare
Summary, in English
Platelets are potent regulators of neutrophil accumulation in septic lung damage. We hypothesized that platelet-derived CXCL4 might support pulmonary neutrophilia in a murine model of abdominal sepsis.
Avdelning/ar
Publiceringsår
2015
Språk
Engelska
Sidor
5347-5359
Publikation/Tidskrift/Serie
British Journal of Pharmacology
Volym
172
Issue
22
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Wiley
Ämne
- Immunology in the medical area
- Anesthesiology and Intensive Care
Status
Published
Forskningsgrupp
- Surgery
- Diabetes - Islet Patophysiology
ISBN/ISSN/Övrigt
- ISSN: 1476-5381