The Intratumoral Distribution of Radiolabeled 177Lu-BR96 Monoclonal Antibodies Changes in Relation to Tumor Histology over Time in a Syngeneic Rat Colon Carcinoma Model.
Författare
Summary, in English
The therapeutic effect of radioimmunotherapy depends on the distribution of the absorbed dose in relation to viable cancer cells within the tumor, which in turn is a function of the activity distribution. The aim of this study was to investigate the distribution of (177)Lu-DOTA-BR96 monoclonal antibodies targeting the Lewis Y antigen over 7 d using a syngeneic rat model of colon carcinoma.
Avdelning/ar
- Medicinsk strålningsfysik, Lund
- Bröstcancer-genetik
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
Publiceringsår
2013
Språk
Engelska
Sidor
1404-1410
Publikation/Tidskrift/Serie
Journal of Nuclear Medicine
Volym
54
Issue
8
Fulltext
- Available as PDF - 902 kB
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Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Society of Nuclear Medicine
Ämne
- Radiology, Nuclear Medicine and Medical Imaging
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0161-5505